TrueCell laboratory and procedure suite

A physician prescribed catalogue of cellular protocols.

The full treatment menu.

Every protocol below is a starting point, not a sales offer. The cell type, dose, and delivery route are decisions made after the specialist physician reviews your case. Many protocols use Muse™ cells — a stress-enduring, pluripotent subpopulation of mesenchymal stem cells. Learn about Muse cells →

Reading the menu

UC-MSC
— umbilical-cord mesenchymal stem cells (Wharton's Jelly).
Muse Cell
— stress-enduring pluripotent MSC subpopulation.
20M / 40M / 100M
— millions of viable cells delivered.
IV
— intravenous.
Intradiscal
— injected into a spinal disc.
PRP
— platelet-rich plasma.
Exosome
— cell-derived signaling vesicles.
01

Joint Therapies

Knee · Hip · Shoulder · Ankle

Knee

We treat your right knee, left knee, or both.

Cells are injected directly into the knee to calm inflammation, support cartilage, and ease the everyday movements that hurt first — stairs, kneeling, getting in and out of a chair.

  • Single UC-MSC 20–30M
  • Single UC-MSC 40–60M
  • Single Muse Cell · IV Homing
  • Single Muse Cell · Direct Injection
  • Single PRP + UC-MSC
  • Single UC-MSC 40M
  • Single Exosome + UC-MSC
  • Both Knees UC-MSC 40M each

Hip

We treat your right hip, left hip, or both — including the joint itself and the bone within.

Used for hip osteoarthritis and avascular necrosis (AVN). The goal is to reduce stiffness, protect the joint surface, and delay or avoid replacement surgery.

  • Single UC-MSC 20–30M / Mild OA
  • Single UC-MSC 40–60M / Moderate
  • Single UC-MSC 100M / AVN
  • Single Muse Cell · IV / AVN
  • Single Muse Cell · Direct
  • Single PRP + UC-MSC
  • Both Hips

Shoulder

We treat the main shoulder joint, the AC joint at the top of the shoulder, and the SC joint near the collarbone — on either side.

Helpful for rotator-cuff injury, early arthritis, and persistent shoulder pain that limits reach, sleep position, or overhead movement.

  • Single UC-MSC 20–30M / Early OA
  • Single UC-MSC 40M / Rotator Cuff
  • Single Muse Cell
  • Single PRP + UC-MSC
  • Both Shoulders

Ankle

We treat your right ankle, left ankle, or both.

Used for ankle arthritis, old sprains that never fully healed, and cartilage damage (OCD lesions) — to restore stability and reduce the daily pain that comes with every step.

  • Single UC-MSC / Mild OA
  • Single UC-MSC / Advanced OA
  • Single Muse Cell
  • Single PRP + UC-MSC / OCD
  • Both Ankles
02

Spine, Sacroiliac & TMJ

Disc · Facet · SI · TMJ

Spine (Back)

We treat the neck (cervical), mid-back (thoracic), and lower back (lumbar) — including the small facet joints that run alongside the spine.

Cells are delivered into discs, facet joints, or the epidural space, depending on whether your pain comes from disc degeneration, joint inflammation, or pinched nerves (radiculopathy).

  • Intradiscal Single Level (UC-MSC)
  • Intradiscal Multi-Level 2–3 (UC-MSC)
  • Intradiscal Muse Cell · NP Regen
  • Facet Joints Bilateral (UC-MSC)
  • Epidural Radiculopathy (UC-MSC)
  • Intradiscal Exosome

Sacroiliac (SI)

We treat the sacroiliac joints — where your lower spine meets the pelvis — one side or both.

Often the hidden cause of low-back, hip, or buttock pain that travels down the leg. Direct injection calms inflammation and restores comfortable movement.

  • Unilateral UC-MSC
  • Bilateral UC-MSC
  • Single Muse Cell

Jaw (TMJ)

We treat the jaw joint on one side or both.

Helpful for clicking, locking, chronic jaw pain, and disc problems that make eating, speaking, or even smiling uncomfortable.

  • Unilateral UC-MSC
  • Bilateral UC-MSC
  • Disc Protocol Muse Cell
03

Hand, Foot & Small Joints

Wrist · Elbow · Foot

Wrist & Hand

We treat the wrist, the knuckle joints (MCP and PIP), and the thumb's base joint (CMC) — on either hand.

For arthritis in the small joints, thumb pain that makes pinching and gripping difficult, and tendon irritation like De Quervain's. The goal is to keep your hands strong for the things you do every day.

  • Wrist · Single UC-MSC
  • Hand / Finger Joint UC-MSC per joint
  • Wrist / Hand Muse Cell
  • Thumb CMC / De Quervain PRP + UC-MSC

Elbow

We treat one or both elbows.

Used for tennis elbow, golfer's elbow, and arthritis — to calm tendon inflammation and restore the pain-free bend and grip you've been missing.

  • Single UC-MSC / OA
  • Tennis Elbow UC-MSC
  • Single Muse Cell
  • Epicondylitis PRP + UC-MSC
  • Both Elbows

Foot

We treat the forefoot joints, the big-toe joint, and the plantar fascia along the bottom of the foot.

Helpful for big-toe arthritis (hallux rigidus), plantar fasciitis, and the chronic foot pain that quietly changes how you walk and stand.

  • 1st MTP / Hallux Rigidus UC-MSC
  • Plantar Fasciitis UC-MSC
  • Foot · Single Muse Cell
  • Plantar PRP + UC-MSC
  • Both Feet
04

IV Systemic Infusion

UC-MSC · Muse · Exosome

Whole-Body Protocols

  • UC-MSC 50M · Anti-inflammatory
  • UC-MSC 100M · High-Dose
  • Muse Cell 1.5×10⁷ · Standard
  • Muse Cell 3.0×10⁷ · High-Dose
  • Exosome Systemic
05

Multi-Joint Packages

Combined-region visits

Combined Protocols

  • Both Knees UC-MSC 40M each
  • Both Knees Muse Cell each
  • Knee + Hip UC-MSC
  • Knee + Hip Muse Cell IV
  • Full Lower Extremity UC-MSC
  • Articular + Muse Cell IV
06

Aesthetic & Vitality

Face · Hair · Skin · Longevity

Facial Rejuvenation

We treat the full face, under-eye area, neck, décolleté, and the backs of the hands.

A regenerative approach to texture, fine lines, and overall radiance — working with your skin's own repair signals instead of adding volume or freezing muscles.

  • Mesotherapy UC-MSC
  • Microneedle Exosome
  • Injection PRP + UC-MSC
  • Topical Exosome serum

Hair Restoration

We treat the crown, hairline, beard, and eyebrows.

Stimulates dormant follicles to support thicker growth and slow further loss. Best for early-to-moderate thinning — not a substitute for transplant once follicles are gone.

  • Scalp PRP + UC-MSC
  • Scalp Exosome microneedle
  • Maintenance Exosome series

Skin & Scarring

We treat acne scarring, stretch marks, burn scars, and surgical scars.

Regenerative signals are delivered into the damaged skin layers to remodel scar tissue and soften the look of indents, marks, and uneven tone over a series of sessions.

  • Local UC-MSC
  • Microneedle Exosome
  • Combined PRP + UC-MSC

Longevity & Vitality

Whole-body protocols supporting energy, sleep, sexual wellness, and graceful aging.

Delivered intravenously to address systemic inflammation and cellular aging — for people who already feel well, but want to feel sharper, recover faster, and age on their own terms.

  • IV UC-MSC 50M
  • IV UC-MSC 100M
  • IV Muse Cell · Standard
  • IV Exosome · Systemic
07

Autoimmune & Inflammatory

RA · MS · Lupus · IBD · Thyroid

Rheumatic

For rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and Sjögren's.

MSCs help recalibrate an overactive immune system — easing joint pain, swelling, and morning stiffness, and often reducing reliance on long-term immunosuppressants.

  • IV UC-MSC 50M
  • IV UC-MSC 100M · High-dose
  • IV Muse Cell · Standard

Connective & Skin

For lupus (SLE), scleroderma, psoriasis, and severe eczema.

Targets the immune-driven inflammation behind skin and connective-tissue flares — often improving both how things look on the surface and what the labs show underneath.

  • IV UC-MSC 50M
  • IV UC-MSC 100M
  • IV Exosome · Systemic

Gastrointestinal

For Crohn's disease, ulcerative colitis, IBS-D, and post-celiac inflammation.

Helps restore the gut lining and quiet the immune response that drives chronic GI symptoms — bloating, urgency, pain, and the fatigue that comes with malabsorption.

  • IV UC-MSC 50M
  • IV UC-MSC 100M
  • IV Muse Cell

Endocrine & Metabolic

For Hashimoto's thyroiditis, Graves' disease, type 1 diabetes, and chronic fatigue.

Used to calm autoimmune attacks on endocrine glands and support metabolic recovery. Works best alongside your endocrinology care, not in place of it.

  • IV UC-MSC 50M
  • IV UC-MSC 100M · High-dose
  • IV Muse Cell
  • IV Exosome · Systemic
08

Neurological & Cognitive

Stroke · Parkinson’s · SCI · TBI · Neuropathy

Stroke & Vascular

For recovery from ischemic and hemorrhagic stroke, and for vascular dementia.

Best started within the first months after the event. Cells support neuroplasticity and circulation in the brain tissue around the injury — working alongside, not replacing, physical and speech rehab.

  • IV UC-MSC 100M
  • IV Muse Cell · High-dose
  • Intrathecal UC-MSC

Neurodegenerative

For Parkinson's, ALS, multiple sclerosis, and early Alzheimer's or mild cognitive impairment (MCI).

The aim is to slow progression and reduce neuroinflammation. A realistic goal is preservation of function — not reversal — and earlier intervention tends to help most.

  • IV UC-MSC 100M
  • IV Muse Cell · High-dose
  • IV Exosome · Systemic
  • Intrathecal UC-MSC

Injury & Trauma

For spinal cord injury, traumatic brain injury, concussion aftereffects, and post-surgical recovery.

Combines IV and intrathecal (spinal fluid) delivery to support nerve repair and reduce the chronic inflammation that lingers long after the initial injury heals.

  • IV UC-MSC 100M
  • IV + Intrathecal UC-MSC + Muse Cell
  • IV Exosome

Peripheral & Pain

For diabetic and chemotherapy-induced neuropathy, idiopathic neuropathy, and complex regional pain syndrome (CRPS).

Targets damaged peripheral nerves to restore sensation and reduce the burning, tingling, or chronic pain that standard medications often can't fully reach.

  • IV UC-MSC 50M
  • IV UC-MSC 100M · High-dose
  • Local UC-MSC + PRP
  • IV Exosome · Systemic

Our process.

No two patients arrive with the same case — so no two protocols leave our clinic identical. Here is how a TrueCell treatment moves from your first conversation to your last follow-up call.

01

Team prep

Your case is reviewed by the specialist physician who will perform your procedure. Cell type, dose, and delivery route are decided around your specific diagnosis — never from a template.

02

Protocol composition

A written protocol is built for your case: cell line, viable cell count, route of administration, and any adjuncts. You see it before you board the plane.

03

Cells flown same-day

Your cells are prepared at GenNova Labs in Guadalajara — an accredited Mexican cell bank — and flown to Tijuana the morning of your procedure. Never frozen on a shelf.

04

Treatment with your team

Every procedure is delivered by a dedicated three-person team assigned to your case: the specialist physician, a nurse, and an anesthesiologist on standby for comfort or pain response. Not shared, not rotating.

05

Monitoring & 3-year follow-up

1–3 days of post-treatment monitoring at your accommodation, then 24/7 reachability with your case manager and the TrueCell team for three full years.

Who this isn't for.

Stem-cell therapy is not the right answer for everyone, and we say so out loud. We turn down candidates whose imaging suggests structural damage past what cells can address — cases where joint replacement or another surgical option will serve them better. We do not treat patients with active malignancy, untreated systemic infection, or uncontrolled coagulopathy.

If we don't believe we can help, we tell you on the consultation call — and where we can, we point you toward the specialist who can. Honest "no" answers are how the "yes" earns its weight.

Get in touch.

Visit

Hospital Blue

Tijuana, Mexico — twenty minutes from San Diego International.

Av. Pacifico 951
Travel

Concierge transfer

Private pickup from SAN. We coordinate lodging and aftercare.

Common questions, answered.

If your question isn't here, our concierge will reply within one business day — no forms, no chase.

How do I book a consultation?

Submit the consultation form with your imaging and history. Our concierge confirms a time within one business day; the consult itself is complimentary and conducted by a board-certified physician.

What does treatment cost?

Single-joint UC-MSC protocols typically begin in the mid-five-figure range; high-dose IV and multi-joint packages are quoted on the consult call once your physician has confirmed the plan. We provide an itemized quote before anything is scheduled.

Will I need follow-up treatments?

Most patients see meaningful improvement from a single visit. Some indications — chronic autoimmune, advanced OA — benefit from a booster at 9–12 months. Your physician will share the expected trajectory during consultation.

Can I combine protocols in one visit?

Yes. Multi-joint and articular-plus-systemic combinations are common and often more efficient. See our multi-joint packages for typical pairings; custom combinations are quoted on consult.

Is travel hard?

Twenty minutes from San Diego International. We arrange private transfer, English-fluent escort, and a curated recovery suite. Most patients need 2–4 nights for a single protocol; multi-joint visits 4–7 nights.

How is the dose decided?

By indication, severity, imaging, and patient size — not by tier. UC-MSC dosing typically ranges from 20M (early OA) to 100M+ (AVN, high-dose systemic). Your physician documents the rationale on your protocol sheet.

Are results guaranteed?

No legitimate regenerative practice will guarantee outcomes. We share aggregate response rates honestly: 84% pain reduction at 6 months, 92% sustained at 12 months. We will tell you if your case is unlikely to respond before you book.

What's included in the price?

Physician consultation, cell preparation, in-clinic procedure, recovery suite, and structured follow-up at 2, 6, and 12 weeks. Travel and lodging are arranged separately by concierge at preferred rates.

"After two years of knee pain and three failed referrals, I'm walking the dog at sunrise again — without thinking about it. Honest expectations, real protocol, lasting result."

DR
David R.
Houston, TX · Knee · UC-MSC 40M

Take the first step.

A physician will review your imaging, diagnosis, and history before recommending anything. If we are not the right answer, we will tell you.

By appointment · Discreet · Complimentary

References — peer-reviewed literature

Citations support the general scientific basis for the regenerative protocols discussed on this page. They do not constitute claims of guaranteed outcomes for any individual patient. Stem cell therapies are not FDA-approved for most conditions; protocols at TrueCell are provided under Mexican regulatory authority (COFEPRIS).

  1. Vega A, Martín-Ferrero MA, Del Canto F, et al. Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial. Transplantation. 2015;99(8):1681–1690. PubMed
  2. Matas J, Orrego M, Amenabar D, et al. Umbilical Cord-Derived Mesenchymal Stromal Cells (MSCs) for Knee Osteoarthritis: Repeated MSC Dosing Is Superior to a Single MSC Dose and to Hyaluronic Acid in a Controlled Randomized Phase I/II Trial. Stem Cells Translational Medicine. 2019;8(3):215–224. PubMed
  3. Pas HIMFL, Winters M, Haisma HJ, Koenis MJ, Tol JL, Moen MH. Stem cell injections in knee osteoarthritis: a systematic review of the literature. British Journal of Sports Medicine. 2017;51(15):1125–1133. PubMed
  4. Lamo-Espinosa JM, Mora G, Blanco JF, et al. Intra-articular injection of two different doses of autologous bone marrow mesenchymal stem cells versus hyaluronic acid in the treatment of knee osteoarthritis. Journal of Translational Medicine. 2016;14(1):246. PubMed
  5. Kuroda Y, Kitada M, Wakao S, et al. Unique multipotent cells in adult human mesenchymal cell populations. Proceedings of the National Academy of Sciences USA. 2010;107(19):8639–8643. PubMed
  6. Filardo G, Previtali D, Napoli F, Candrian C, Zaffagnini S, Grassi A. PRP Injections for the Treatment of Knee Osteoarthritis: A Meta-Analysis of Randomized Controlled Trials. Cartilage. 2021;13(1_suppl):364S–375S. PubMed
  7. Centeno CJ, Al-Sayegh H, Bashir J, Goodyear S, Freeman MD. A multi-center analysis of adverse events among two thousand, three hundred and seventy two adult patients undergoing adult autologous stem cell therapy for orthopaedic conditions. International Orthopaedics. 2016;40(8):1755–1765. PubMed

Enjoy a complimentary video call with one of our physicians.

Dr. Raúl López Serna